Preventing False Positives in Targeted Analytical Methodologies:
A Must-Read for Analytical Scientists
False positives in nitrosamine analysis can lead to costly missteps and regulatory complications—yet many labs still rely on generic methods that put data integrity at risk.
In this insightful presentation, Nathanael Page of Resolian outlines why a one-size-fits-all approach falls short and how tailored method development can significantly reduce the risk of false positives.
From identifying critical sources of analytical error to exploring the importance of chromatographic selectivity and HRAMS techniques, this document offers a practical, expert-led guide to more accurate, reliable results.
Download the full presentation to explore Resolian’s proven strategies for precision and confidence in nitrosamine testing.

Topics Covered
Strategic Considerations for Adopting Oligonucleotide Therapies
- Identifying potential sources of false positives during the development of analytical methods.
- Approaches to mitigate the risk of false positives during the development of analytical methods.
- Considerations for the utilisation of High Resolution Accurate Mass Spectrometry in confirmatory nitrosamine analysis.
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