High Resolution Mass Spectrometry (HR-MS)
Sharper Detection. Richer Data. Faster Decisions.
State-of-the-art HR-MS technology backed by 50+ years of bioanalytical experience, from discovery through GCP clinical trials.Building on 50+ years of experience providing bioanalytical services, and 20+ years working to GLP and GCP, Resolian continues to invest in the latest High Resolution Mass Spectrometry (HR-MS) technology.
Reach out to us directly to learn more about Resolian’s High Resolution Mass Spectrometry services.
High Resolution Mass Spectrometry – Why Is It Beneficial?
- Reduced background noise and interference can allow lower detection limits to be achieved and generation of more robust data
- With a more selective mass-based detection, sample preparation techniques can be simplified, leading to faster method development and more robust assays
- Acquisition of full scan data enables faster MS optimization and the ability to interrogate data post-run for enhanced troubleshooting ability
- High resolution allows for the intact analysis of proteins, informing on their in vivo catabolitic fate
Integrated Support from Early Discovery to Late-Phase Clinical Trials
Beyond specialist HR-MS experience, Resolian’s dedicated LC-MS team offers integrated support from early discovery to late-phase clinical trials, advising you on the regulations applicable to your project.
Resolian’s integrated services include:
- Fast method development for discovery compounds
- Method development and validation for GLP TK studies and GCP clinical trials
- Fast turnaround for phase I clinical studies
- Pharmacokinetic data analysis using validated software systems (e.g., WinNonlin)
- Logistical support for clinical sample management including sample collection kit production and supply of sampling kits, labels, investigator manual and shipping
- Data management using LIMS or specialist software
Ready to unlock the advantages of high resolution mass spectrometry?
Partner with an experienced HR-MS team that delivers lower detection limits, simplified sample preparation,
and integrated support from early discovery to late-phase clinical studies.
Our Bioanalytics Resources
Case Studies
Measuring What Matters: High-Precision Plasma Protein Binding Assessment for Highly Bound Compounds Under ICH M12
Case Studies
Solving Carboplatin: A Novel LC-MS/MS Assay for Intact Drug Quantitation in Human Plasma
Blog, Publications
When AI Meets Experimental Biology: Supporting Breakthrough Peptide Research
Case Studies
Developing and Validating a Simple, Rapid LC-MS/MS Method for Semaglutide in Human Plasma
