Our Research

Discover our recent findings, catch up with news, and review in-depth resources.

Case Studies

Development and Validation of Immunogenicity Assays for ADCs

CASE STUDY – Addressing ADC Regulatory Challenges by Providing Validated Assays for Multi-Domain Proteins…
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Case Studies

Development and Validation of an Immunogenicity Assay for Detection of Anti-AAV Antibodies

CASE STUDY – ANTI-AAV ANTIBODIES. We are experienced with a wide range of different proteins and therapeutics…
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Blog

Pharmacokinetics (PK) Urine Analysis

Whereas blood is collected for analysis at a discrete time point, urine is collected over periods of time known as collection intervals…
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Case Studies

Challenges of Developing an ADA Assay for Bispecific Antibody Therapeutics and ADA Characterization

Bispecifics (Bs) are biopharmaceutical products that bind to two different targets (epitopes). These are mainly two types: IgG-like (antibodies Abs) and non-IgG-like which include Bites (bispecific T-cell engager) and DARTs (Dual-affinity Re-targeting Antibody)…
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Blog

What Makes a Good LC-MS/MS Bioassay?

Liquid chromatography linked to tandem mass spectrometry (LC–MS/MS, LC-MS) is the “go-to” method for pharmacokinetics and metabolism studies across drug development with recent advances in separation, throughput and methods for analyzing protein biotherapeutics…
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Videos

Beyond the Abstract: An Interview with Ashley Phillips

In this Bioanalysis Zone podcast episode, our Senior Scientist and Technical Specialist Ashley Phillips discusses his recent publication…
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Zhiyang Zhao, Ph.D.

Chief Scientific Officer

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Zhiyang Zhao, Ph.D., serves as Chief Scientific Officer (CSO) at Resolian. Dr. Zhao has over 30 years of pharmaceutical industry experience with special focus on drug metabolism and bioanalysis of small and large molecules in drug discovery and development. Dr. Zhao has previously held positions at Pfizer, GlaxoSmithKline, and Amgen. Before joining Resolian in 2015, Dr. Zhao served as Site Director of Preclinical Research at Amgen in Cambridge, Massachusetts, for over a decade. 

Currently, Dr. Zhao serves as an Adjunct Professor at the Eshelman School of Pharmacy of the University of North Carolina at Chapel Hill, North Carolina, and as Editor-in-Chief of Drug Metabolism & Bioanalysis Letters, a journal by Bentham Science, which publishes in all areas of drug metabolism and bioanalysis. Dr. Zhao received his Ph.D. degree in Medicinal Chemistry from Virginia Polytechnic and State University (popularly known as Virginia Tech) in Blacksburg, Virginia. 

 

Patrick Bennett

Chief Executive Officer

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Patrick Bennett has over 35 years of experience in pharmaceutical analysis and laboratory management. Now Chief Business Officer at Resolian, Patrick’s experience includes the roles of Strategic Marketing Director for Pharma with Thermo Fisher Scientific, LabCorp, and Vice President of Strategy and Development with PPD. 

Patrick earned a B.S. degree in Toxicology and a M.S. degree in Pharmacology from the College of Pharmacy and Allied Health at St. John’s University and an M.B.A in International Marketing from the Martin J. Whitman School of Management at Syracuse University.